PO-0730 NTCP model for penetration/aspiration after (chemo)radiation including DVH parameters.

DVH- and NTCP-based dosimetric comparison of different longitudinal margins for VMAT-IMRT of esophageal cancer

PURPOSE To cover the microscopic tumor spread in squamous cell carcinoma of the esophagus (SCC), longitudinal margins of 3-4 cm are used for radiotherapy (RT) protocols. However, smaller margins of 2-3 cm might be reasonable when advanced diagnostic imaging is integrated into target volume delineation. Purpose of this study was to compare the dose distribution and deposition to the organs at ri...

Investigating of relationship between the parameters related to the treatment planning and the biological parameters in radiation induced pneumonitis in breast cancer patients

Introduction: The purpose in this study is to analyze of DVH parameters as predictors of radiation pneumonitis and investigation on the relationship between dosimetric and clinical parameters based on PFTs as response in NTCP model and therefore achieve to lung dose- response relation in breast cancer patients. Prescribed dose to treatment volumes was 50 Gy in 2.0 Gy/fractions ...

Clinical parameters model for predicting pathologic complete response following preoperative chemoradiation in patients with esophageal cancer.

BACKGROUND Approximately 25% of patients with esophageal cancer (EC) who undergo preoperative chemoradiation, achieve a pathologic complete response (pathCR). We hypothesized that a model based on clinical parameters could predict pathCR with a high (≥60%) probability. PATIENTS AND METHODS We analyzed 322 patients with EC who underwent preoperative chemoradiation. All the patients had baselin...

A Model Category for Local Po-spaces

Locally partial-ordered spaces (local po-spaces) have been used to model concurrent systems. We provide equivalences for these spaces by constructing a model category containing the category of local po-spaces. We show the category of simplicial presheaves on local po-spaces can be given Jardine’s model structure, in which we identify the weak equivalences between local po-spaces. In the proces...

A case for po-manifolds - in chase after a good topological model for concurrency